An Annotated Review Erythrocyte Enzymopathies, Hemolytic Anemia, and Multisystem Disease
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منابع مشابه
Erythrocyte enzymopathies, hemolytic anemia, and multisystem disease: an annotated review.
T HE CLINICAL EFFECTS of erythrocyte enzymopathies vary widely in humans. In some, such as glyoxalase II deficiency,’ there are no apparent clinical mani festations, hematologic or otherwise. The ability to convert methylglyoxal to lactate, therefore, may have little or no role in human metabolism. In other enzymopathies, there are no hematologic manifestations, but the red cell shares an abnor...
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Abstract Background: Hereditary red cell enzyme disorders are a group of Non-immune/Spherocytic Hemolytic Anemia, although these disorders are rare and they have not public health problems, the detection of these defects could help to physician in treatment and differential diagnosis. This study evaluated 5 enzymopathies in patients with Hereditary Non –immune/Spherocytic Hemolyti...
متن کاملThe energy-less red blood cell is lost: erythrocyte enzyme abnormalities of glycolysis
The red blood cell depends solely on the anaerobic conversion of glucose by the Embden-Meyerhof pathway for the generation and storage of high-energy phosphates, which is necessary for the maintenance of a number of vital functions. Many red blood cell enzymopathies have been described that disturb the erythrocyte’s integrity, shorten its cellular survival, and result in hemolytic anemia. By fa...
متن کاملThe energy-less red blood cell is lost: erythrocyte enzyme abnormalities of glycolysis.
The red blood cell depends solely on the anaerobic conversion of glucose by the Embden-Meyerhof pathway for the generation and storage of high-energy phosphates, which is necessary for the maintenance of a number of vital functions. Many red blood cell enzymopathies have been described that disturb the erythrocyte's integrity, shorten its cellular survival, and result in hemolytic anemia. By fa...
متن کاملMultiple splenic infarctions in a dog with immune-mediated hemolytic anemia: therapeutic implications
Background: Splenic infarction (SI) is a rare clinical entity seldom encountered in veterinary medicine. Its most frequent causes include thromboembolic status, splenomegaly, and cardiac disease. Although thrombotic elements from the circulation provide the most common context for thromboembolic SIs, immune-mediated hemolytic anemia (IMHA) has not been reported as an underlying...
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تاریخ انتشار 1984